Gel capsules make reactions with organolithiums simpler and safer

Gel

Source: © Petr Slavík et al

Low-cost gels improve the handling and storage of traditionally dangerous organometallics, expanding applications and possibilities in synthesis

Low-cost gels have improved the stability of organolithium reagents, making manipulation simpler and safer. Thanks to this innovative encapsulation method, these reactive compounds – usually sensitive to moisture and air – survive storage under ambient conditions for over 25 days. Moreover, these gel capsules work with other organometallic reagents, such as Grignards, hinting at additional attractive applications protecting pyrophoric compounds and hazardous chemicals.