All Drug formulation and delivery articles
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NewsAir jet gun delivers needle-free vaccines in MOFs without any need for refrigeration
Release rate of injector system can be fine-tuned by changing the carrier gas
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Research
The hunt is on for vaccine ingredients that don’t come from wild sharks
Yeast can provide the raw materials and chemical wizardry can transform them
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Business
Encoding creativity in drug discovery
Machine learning can complement and reinforce human intuition and experience
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Sponsored
Thermal analysis in the development of long-acting injectable systems
Evaluating new polymers for slow-release drug delivery could deliver better treatment for patients
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Feature
Tiny delivery systems for cancer drugs
Encapsulating anticancer agents in nanoparticles can make them gentler on the rest of the body. Clare Sansom reports
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Business
An evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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News
Software from Cambridge crystallographic experts could save pharma industry millions
Informatic tools will help drug formulators understand particle behaviour in their final product
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Opinion
May cause side effects
The dose makes the poison, but understanding unwanted drug interactions is complicated
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Research
Light-activated cancer treatment uses tumour-targeting enzymes to cut side effects
Enzymatic activation of a photosensitive prodrug in cancerous cells shows promise in mice
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Business
What is the future of Covid-19 pharmaceuticals?
Firms anticipate long-term markets for prevention and treatment
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Research
Edible, fluorescent silk tags could help stem tide of counterfeit medicines
Marker could be a simple answer to ensuring provenance of drugs
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Business
Moderna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents
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Research
Sulfonated macrocycle helps the medicine go down
A supramolecular approach makes alkaloid drugs taste less bitter
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Research
Engineered antibody that snags sperm could be an effective non-hormonal contraceptive
Approach could offer new method of contraception for women
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Feature
mRNA vaccines for Covid and beyond
Already hailed as a miracle, the new vaccine technology could protect us from other diseases, Clare Sansom finds
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News
First malaria vaccine approved as hopes raised for new, better ones
Mosquirix prevents just 30% of severe malaria cases in young children prompting a guarded welcome
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Research
Programmable peptoid template for disrupting protein–protein interactions inside cells
System optimises residues involved in binding target independently from those that promote membrane permeability
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Research
Neural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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Business
Developing countries sidelined in Covid-19 vaccine scramble
Lack of funds and local manufacturing capacity has prevented Covax from competing with wealthier nations’ self-interest
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Business
Sartan contaminant recall hits generics manufacturers
Three European suppliers recalling multiple batches of medicines owing to active ingredient contamination
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